Article in press

December 2017

Volume 2  Issue 1

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Case Report

Laparoscopic-Assisted Trucut Biopsy for the Diagnosis of Linitis Plastica

Gamal E H. A. El Shallaly*FRCSEd, MFSTEd, MMAS (Dundee), CertTHE(Dundee)

Linitis plastica is a type of adenocarcinoma of the stomach that is both rare and difficult to diagnose and has poor prognosis. Median survival is 6-8 months and the 5 year 8% (3-10%). Unlike other types of adenocarcinomas that can readily be identified at endoscopy as an ulcerative, flat, or polypoid lesions, the features of this cancer are so subtle that it can be missed unless a high level of suspicion is practiced.

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Research Article

Influence of the Display Field of View in Low-dose Computed Tomography on Airway Measurements

Sadahiro Nakagawa* BSc, Akira Yanagisawa BSc, Koji Takahashi MD PhD

Chronic obstructive pulmonary disease, which is characterized by the presence of airflow limitation that is not fully reversible, includes small airway disease and emphysema. The use of high-resolution volume data in the initial and follow-up assessment of patients with chronic obstructive pulmonary disease has facilitated airway measurements of the lung. However, according to ALARA (As Low As Reasonably Achievable) principles, the radiation dose for the computed tomography (CT) protocol for airway analysis should be as low as possible for reasonably achieving effective imaging because radiation-induced carcinogenesis is a stochastic effect.

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Research Article

Tau and Pet/Mri Imaging Biomarkers for Detecting and Diagnosing Early Dementia

Yongxia Zhou, Ph.D.*, Bing Bai, and For the Alzheimer’s Disease Neuroimaging Initiative

Specific objective of this project is to quantify the neuropathological tau depositions in brain regions and to investigate primary age-related tau pathology and associations with amyloid and glucose-metabolism, neurocognitive tests and MRI metrics. Preliminary results demonstrated higher temporal deposition especially in the hippocampus and the inferior temporal regions compared to mean cortical deposition. Quantitative Braak stage-based regional analyses found highest tau deposition in the Braak stage II in the preclinical samples.

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Research Article

Development and Testing of a Hybrid Synthetic-Biologic Phantom for the Optimization of Mr Sequences for Articular Cartilage

Alessandro Marinetti, Francesco Tessarolo*, Alessandro Cristoforetti,Fabrizio Cortese, Sabino Walter Della Sala

Magnetic resonance imaging (MRI) has proved to be an effective non-invasive diagnostic tool in the assessment of articular cartilage. Accuracy of cartilage MRI has been improved in the last decade by developing cartilage specific sequences. The use of high-field magnetic resonance (MR) scanners with increased signal-to-noise ratio, allowed increasing spatial resolution and acquisition times.

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