Editor note: Cell and Molecular Biology
Vickram Sundaram* Ph.D, PDF
School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, India
*Corresponding author: Vickram Sundaram, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, India
This Journal aims at publishing dependable source of information on the discoveries and current developments related to Cell and Molecular Biology. This journal covers topics like Cell and Systems Biology, Cell Physiology, Biochemistry, Genetics/Gene Regulation, Genomics/Proteomics, Computational Biology, Microbial Pathogenesis, Immunology, Molecular Mechanisms of Disease, Cancer Biology.
This journal of cell and molecular biology of volume 1 and issue 2 published articles discussing topics like studying the influence of Thymoquinone on the unfolding transition of human serum albumin , reviewed topics on Anti-inflammatory agents and their role in Atherosclerosis and growth factors as a supportive treatment in chemotherapy , and lastly, an article studying the assessment of individual sperm proteins as a reliable method for identification of the cryopreservation technique .
Thymoquinone is a phytochemical compound present in the plant known as Nigella sativa utilized in producing an essential oil. Zeyad et al. ., presented a research article studying the influence of Thymoquinone on the unfolding transition of human serum albumin. The effect of thymoquinone (TQ) on the conformational stability of human serum albumin (HSA) at temperatures range of 25 – 50 °C has been investigated by means of fluorescence spectroscopy. It is found that occupancy of HSA specific binding site by TQ strongly hinders the unfolding of HSA to about 3.25 M urea concentration and at low temperature. Hence, concluded that the TQ acts as a stabilizing agent and cause enough impact against denaturation by urea in the temperature range studied.
Timothy Allen et al. ., reviewed and presented article on Anti-inflammatory agents and their role in Atherosclerosis. It is a chronic disease, with the process of narrowing and hardening of arteries, related with other cardiovascular diseases. However, an inflammation plays a key role in the progression and development of atherosclerosis. Therefore, it can be reduced by various anti-inflammatory types of drugs. Different clinical trials stated that these drugs like Niacin, flavonoids, and aspirin have the lipid lowering properties and it decreases the chances of cardiovascular risk because of its anti-inflammatory actions. This review concluded the anti-inflammatory agents with their role in the treatment however, still there is much more research studying the impact of anti-inflammatory drugs along with their role in the treatment of atherosclerosis.
Timothy Allen et al. ., presented review article discussing on growth factors as a supportive treatment in chemotherapy. Even with lot of advancements in treatment patterns still there are dose-limiting toxicities linked with chemotherapy. This indicates that there is need of supportive care treatments to assist the cytotoxic drugs. However, the main aim of supportive drug is not only to relieve the pain but also to improve the quality of living. Growth factors are peptides with low molecular weight and are active in various stimulation of cell processes. These small molecules are utilized as a supportive treatment to control and decrease the toxicity of chemotherapeutic treatment. These growth factors may include GM-CSF, G-CSF, and erythropoietin. The applications of these therapeutic agents as the supportive care treatment have been discussed in this article.
Spermatozoa cryopreservation is an integral part of assisted reproductive technology, which is used for the management of infertility and some other medical conditions. Mohamed et al. ., divulged research article on assessment of individual sperm proteins as a reliable method for identification of the cryopreservation technique. Various cryopreservation procedures have been introduced. The most frequently applied techniques for comparing these procedures are subjective and objective cellular biology techniques. This manuscript represents the author’s viewpoint regarding the significance of applying the molecular biology assessment of proteins as markers of physiological parameters and fertilizing ability of post-thawing spermatozoa.
For more information: https://jacobspublishers.com/jacobs-journal-of-cell-and-molecular-biology-issn-2381-2761
- Yasseen ZJ, Hammad JH, AL Talla HA. Influence of Thymoquinone on the Unfolding Transition of Human Serum Albumin. J J Cell Mol Bio. 2015, 1(2): 1-6.
- Allen T, Giridhar MNV, Razavi GSE. Anti-Inflammatory Agents and their Role in Atherosclerosis. J J Cell Mol Bio. 2015, 1(2): 1-15.
- Allen T, Giridhar MNV, Razavi GSE. Growth Factor as a Supportive Treatment in Chemotherapy. J J Cell Mol Bio. 2015, 1(2): 1-8.
- Mohamed MSA. Assessment of Individual Sperm Proteins as a Reliable Method for Determination of the Cryopreservation Technique of Choice. J J Cell Mol Bio. 2015, 1(2): 1-4.