Editor note: Ophthalmology

Editor note: Ophthalmology

Sneha Pasupati*, Ph.D

Department of Bioinformatics, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, India

*Corresponding author: Sneha Pasupati, Department of Bioinformatics, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, India

The Journal of Ophthalmology covers all areas of ophthalmology, including basic science investigations and clinical studies supporting the scientific innovation and advancement in Ophthalmology research community.

The Journal of Ophthalmology of volume 1 issue 1 published articles on myelin purified from optic nerve to study whether it plays an energetic role for the retinal ganglion cells (RGC) axons [1], presented a case report of one patient with rapidly growing eyebrow pilomatrixoma with strong Bcl-2 following trauma, which was not mentioned before [2], documented on comparative studies outcome of Epiretinal Membrane Surgery, duration of Surgery with and without the use of trypan blue dye [3] and lastly, on outcomes of Dacryocystorhinostomy carried out by an orbit and oculoplastics fellow at the Arvind eye hospital, Madurai, India [4].

Myelin is a lipid-rich substance formed in the central nervous system (CNS) by glial cells called oligodendrocytes, and in the peripheral nervous system (PNS) by Schwann cells. Myelin from both central and peripheral nervous system was shown to express functional FoF1-ATP synthase and respiratory chain complexes that conduct an aerobic metabolism, to support the axonal energy demand. In this work, Silvia Ravera et al. [1]., focused on myelin purified from optic nerve to study whether it plays an energetic role for the retinal ganglion cells (RGC) axons. Isolated Myelin (IM) from bovine optic nerve was assayed for respiratory and ATP synthetic properties by biochemical and confocal microscopy techniques. The presented work extends previous data on CNS and PNS myelin to the optic nerve, which consumes the greatest share of oxygen in the body. In future, this would also be supported by several proteomic studies.

Pilomatrixoma is a benign cutaneous neoplasm that arises from matrix cells of hair follicle. It is a superficial, firm, solitary, slow-growing, painless dermal mass in the head and neck region, including the eyelid or eyebrow. Rapidly growth pilomatrixoma is rare and have been reported following trauma. Herein, Yu-Yun Huang et al. [2]., presented a case report of one patient with rapidly growing eyebrow pilomatrixoma with strong Bcl-2 following trauma, which was not mentioned before. However, the etiology of pilomatrixoma is not completely understood. Human and animal studies have shown that Bcl-2 proteins are increased after traumatic insults. It is possible that increased expression of Bcl-2 after trauma promotes cells proliferation by regulating apoptosis and contribute to the development of pilomatrixoma. Hence, the cause of effecting relationship between trauma and pilomatrixoma still remains to be studied and established.

  1. Heitz et al. [3]., documented on comparative studies outcome of Epiretinal Membrane Surgery and duration of Surgery with and without the use of trypan blue dye. The results of this study show that using systematically blue dye in epiretinal membrane surgery is beneficial for two reasons. First, patients with Epiretinal Membrane Surgery with high myopia, have better visual outcomes and reduced the surgery by 11 min, corresponding to a 24% reduction in the mean operating time and helped with increased number of daily surgeries.

Dacryocystorhinostomy (DCR) is termed to a surgical procedure to restore the flow of tears into the nose from the lacrimal sac when the nasolacrimal duct does not function. Andre Omgbwa Eballe et al. [4]., presented a report on outcomes of Dacryocystorhinostomy carried out by an orbit and oculoplastics (surgical procedure dealing reconstruction of eye and its parts) fellow at the Arvind eye hospital, Madurai, India. From obtained results a long-term follow up of external DCR patients operated by a fellow, can give a better view on complications to improve skills.

For more information: https://jacobspublishers.com/jacobs-journal-of-ophthalmology-issn-2469-3057

Reference

  1. Ravera S. Oxydative Metabolism in Optic Nerve Myelin: New Perspectives in Hereditary Optic Neuropathies. J J Ophth. 2014, 1(1): 003.
  2. Tsai CC. Bcl-2 Immunoexpression in Rapidly Growing Eyebrow Pilomatrixoma after Blunt Trauma. J J Ophthalmol. 2014, 1(1): 004.
  3. Gaucher D. Epiretinal Membrane Surgery With and Without a Systematic Use of Blue Dye: Functional Outcome and Surgery Duration. J J Ophthalmol. 2015, 1(1): 006.
  4. Eballe A O. Early Outcomes of External Dacryocystorhinostomy Done by an Orbit and Oculoplastic Fellow at the Aravind Eye Hospital, Madurai, I J J Ophthalmol. 2015, 1(1): 007

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