Internal Medicine

Editor note

Internal Medicine

Corresponding author: Niharika Mandal, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, India

Jacobs Journal of Internal Medicine is a peer-reviewed medical journal dealing with all aspects of internal medicine such as prevention, diagnosis, and treatment of diseases with clinical pharmacy and veterinary medicine.

Journal of Internal Medicine Volume 2 Issue 1 published articles examining Protocol for a randomised, multicentre, double blinded phase iii study of perioperative ketorolac in women of African descent with operable breast cancer [1], dynamometer measurements of grip strength in frail elderly inpatients [2], and prostate specific antigen (psa) derivatives for diagnosis of prostate cancer and benign prostatic hyperplasia subjects in Sokoto, Nigeria [3].

Cancer remains one of the leading causes of morbidity and mortality worldwide and Breast cancer is the most common form of malignancy occurring in women around the world. Romano Demicheli et al. [1]., studied protocol for a randomised, multicentre, double blinded phase III study of perioperative ketorolac in women of African descent with operable breast cancer. Author studied protocol to outline the procedure for a randomised, multicentre, double blinded phase III study of perioperative Ketorolac in Women of African Descent with Operable Breast Cancer. The typical type of breast cancer in sub Saharan Africa is triple negative breast cancer (TNBC) and is usually considered the worst early breast cancer diagnosis since there are no known targeted therapies and patients often relapse and die early.

Sarcopenia and frailty are two clinical entities that generate loss of independence. Sarcopenia is characterized by loss of skeletal muscle mass and strength and is a risk factor for fragility and physical disabilities. M Rosario Beseler Soto. [2]., presented Dynamometer Measurements of Grip Strength in Frail Elderly Inpatients. In elderly frail patients, there is generalized weakness in grip strength and in lower extremities. A statistically significant relation exists between dynamometric grip strength and the lower limbs strength analyzed with manual muscle test. Authors conclude that with a simple and economical method is objectively possible to approach the lower limbs strength in frail elderly inpatients whose cooperation is very limited and thus establish therapeutic programs to improve their physical function.

The outstanding successes achieved in the treatment of prostate cancer should be credited to the “golden five” of this era, namely imaging, radiation, chemotherapy, surgery and screening programs. Nnamah et al. [3]., the use of PSA derivatives has the potential to improve upon the current performance characteristics of the PSA test alone. An improved screening test may dramatically reduce the number of men undergoing an unnecessary biopsy and simultaneously enables clinicians to focus on high-risk cases of localized prostate cancer in a population of men likely to benefit from radical intervention.

For more information: https://jacobspublishers.com/december-2016-volume-2-issue-1-internal-medicine/

The Journal welcomes articles from all the fields related to Internal Medicine.

Reference:

  1. Romano Demicheli, Erhabor Osaro*, Michael Retsky,Forget Patrice,Vaidya Jayant S, Bello SO. Protocol For A Randomised, Multicentre, Double Blinded Phase III Study Of Perioperative Ketorolac In Women Of African Descent With Operable Breast Cancer.
  2. M Rosario Beseler Soto. Dynamometer Measurements of Grip Strength in Frail Elderly Inpatients.
  3. Nnamah*, NK ,Anaja, PO ,Mungadi, IA and Bilbis,LS ,Dallatu,MK. Prostate Specific Antigen (PSA) Derivatives for Diagnosis of Prostate Cancer and Benign Prostatic Hyperplasia Subjects in Sokoto, Nigeria.

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