Addiction Disorders and Therapy

Implications of Substance Use in Patients with Cystic Fibrosis: A Review

Published on: 2019-04-02


Substance use and substance use disorders are very common, with high personal and societal costs. With increases in life expectancy, substance use has become more commonly identified in individuals with cystic fibrosis (CF). Problem substance use has special implications for those with CF, including effects on the respiratory system, decreased adherence to medical treatments, and perhaps increased mortality. In the present review, we discuss commonly used substances including alcohol, tobacco, marijuana, opioids and benzodiazepines. We also discuss developmental considerations for substance use in adolescents and young adults with CF as well as special considerations for those undergoing transplantation.


Substance use; Cystic fibrosis; Adolescence