Addiction Disorders and Therapy

Evaluation of abuse drugs tests variations in fresh biological samples of abusers

*Majid Rezaei Basiri
Department Of Pharmacology And Toxicology, Tabriz University Of Medical Sciences, Iran, Islamic Republic Of

*Corresponding Author:
Majid Rezaei Basiri
Department Of Pharmacology And Toxicology, Tabriz University Of Medical Sciences, Iran, Islamic Republic Of
Email:basiri@alumnus.tums.ac.ir

Published on: 2019-02-12

Abstract

Background and Aim: In this study N=450 fresh blood and urine samples of male abusers were employed to distinguish abuse drugs and some treatment drugs. All of the study population were male and their age range was Mean ±SD = 40±20. All study population filled satisfy form to participating in study.
Methods: Some of abuse drugs were distinguished in this study which were Heroin, Morphine, Cannabis, Methadone, Tramadol, Beprexin, Amphetamine, Metamphetamine, MethylenDioxy metamphetamine, Cocaine, Phencyclidine, Benzodiazepine, Three cyclic antidepressant, Phenobarbital… The diagnosis tests methods were determined by abusers’ dependency on treatment conditions. All data were collected and analyzed by one-way ANOVA and t-test before and after detoxification.
Results: When comparing the test results p-value 0≥0.05 was considered as significance level. Treatment duration follow-up of all blood and urine samples of the abusers indicated negative results. The results of this study showed that the blood samples of abusers are suitable to indicating positive results.
Conclusion: According to the findings of the present investigation rapid strip tests were useful in blood samples and TLC was accessible confirmation method to abusers’ urine samples. We purpose that this method will be suitable to distinguish of abuse drugs in other biological samples in future.

Keywords

Abusers; Fresh Biological Samples; Rapid Strip Tests; Detoxification; Thin Layer Chromatography

Introduction

Today, addiction epidemy has changed to serious social challenge and problem even in developed countries and in the poor societies social damages are consequences of increased addicted population. Statistical studies and appropriate treatment and diagnosis methods will be highly efficient in line with prevention of increasing addicted population. Scientific progress and advent of new sciences have resulted in production of new kinetic addictive substances in industrial communities. This is while during recent decades’ addiction epidemy used to involved traditional substances such as opium. Different studies have been conducted in western and weak countries in line with diagnosis, treatment and prevention of traditional and industrial addictive substances and still they are conducted currently. It seems that fast and cost-effective methods are important in addiction control and inhibition process. Based on new studies, use of fresh biologic sample of the addicted people has been proposed [1,2,3].