Compliance of Finnish Male CHD and Total Mortality with Soil Fertilization in 1957- 1990
Published on: 2018-10-15
Magnesium (Mg) tissue content has been associated with vascular pathology and risks of coronary heart disease (CHD). Associations between fertilization, morbidity and mortality have been studied in veterinary, but less in human medicine. In this study we assessed changes in male (M) CHD and total (TOT) (mortality) and their regressions by fertilization parameters: calcium (Ca), Mg, potassium (K), phosphorus (P), nitrogen (N) and carbonate (CO3) (direct or functions of these parameters) in 1957-1990, when medical treatments were less effective than today. Fertilization parameters are given as equivalents/ha. The aim of this study is to assess whether mutual ratios of mineral elements in fertilization of Finnish agricultural soils were associated with male TOT and CHD. Results (Regressions by) [Mg/(Ca+Mg+K)] and (combined regressions by) [Ca;Mg;K], [CO3;Mg;K] and [N;P;K] explained highly significantly (p < 0.001) and remarkably variation in TOT (94-98 %) and in CHD (57 - 81 %). In the represented combined regressions coefficients by mineral elements promoting Mg uptake (Mg and N) were negative, by mineral elements reducing Mg uptake (Ca, CO3, K and P) generally positive. Conclusion The mutual variation in the amounts of Ca, CO3, Mg, K, P and N fertilizers of Finnish agricultural soils in 1957-1990 explained significantly TOT and CHD mortality. Effects of Mg on 300 enzymes could explain its primary effect on TOT and secondary effect on CHD. These associations could be mediated through Mg variation in basic food.