Jacobs Journal of Anatomy and Physiology

Deviant Cellular and Physiological Responses to Exercise in Myalgic Encephalomyelitis and Chronic Fatigue Syndrome

Published on: 2016-10-21

Abstract

Post-exertional “malaise” is a hallmark symptom of Myalgic Encephalomyelitis (ME) and Chronic Fatigue Syndrome (CFS). Various abnormalities, including abnormal physiological responses to exertion, can account for post-exertional “malaise” and “exercise avoidance”. Since these abnormalities are not observed in sedentary healthy controls, the abnormalities and deviant responses cannot be explained by “exercise avoidance” and subsequent deconditioning, nor by psychogenic factors.

Keywords

Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Exercise Physiology, Energetics, Immune System, Oxidative And Nitrosative Stress