Jacobs Journal of Anesthesiology and Research

A Combined Bolus-Infusion Approach over Pure Bolus Regime in Stabilizing Hypotension and Maintaining Consciousness in A Case of Methadone Poisoning

Published on: 2017-05-15

Abstract

Naloxone is an opioid antagonist that competitively binds to opioid receptors and reverses their effects. It is indicated for use in respiratory depression caused by opioid overdose. We provide a case study approach to discuss the advantages of employing a combined Naloxone bolus- infusion administration to stabilize blood pressure and maintain responsiveness during the critical care phase of treatment.

Keywords

Methadone, Overdose, Naloxone, Bolus, Infusion