Jacobs Journal of Anesthesiology and Research

Dexmedetomidine: An Update of its Pharmacology and Clinical Practice

Published on: 2017-07-31


Surgery and post-operative stress cause an highly risky hyperdynamic state, especially in the cardiovascular patient. In cardiac surgery increased myocardial oxygen demand can have serious sequelae, including death. The effective use of sedative-hypnotic agents and analgesics is an integral part of comfort and safety of the patients. Dexmedetomidine was approved as the most recent agent belonging to this group and was introduced into clinical practice as a short-term sedative.


Dexmedetomidine; alpha2 Agonist; Cardiac Surgical Patient; Post-Operative Delirium; Conscious Sedation