Jacobs Journal of Bone Marrow and Stem Cell Research

All Immature Cells Develop in to Fetal Stem Cells: A Myth or a Fact

*Charitha Burri
Department Of Stem Cell Research, Siddhartha Institute , Jawaharlal Nehru Technological University, Hyderabad, India

*Corresponding Author:
Charitha Burri
Department Of Stem Cell Research, Siddhartha Institute , Jawaharlal Nehru Technological University, Hyderabad, India
Email:charithaburri5@gmail.com

Published on: 2018-06-22

Abstract

Over the last several years it has become increasingly understood by researchers and clinicians that the clinical efficacy of utilizing Mesenchymal Stem Cells to treat discogenic pain is not dependent on the cells differentiating into Nucleus Pulposus cells but entirely on their paracrine release of growth factors and exosomes. Living MSCs are not required to accomplish the release of GFs and exosomes into a disc. The purpose of this paper is to introduce the concept of using acellular MSC exosome products and the rationale of why acellular will replace all current cellular therapies both autogenous and allogeneic for the treatment of discogenic pain.

Keywords

Introduction

Stem cells:

Stem cells are the somatic cells of the body which can split and become segregated. The stem cells perform a special role in the growth of an organism. Developed tissues like skin, muscles, blood have various types of cells.

Types of stem cells:

  • Embryonic stem cells
  • Somatic or Adult stem cells
  • Induced pluripotent Stem Cells
  • Amniotic fluid stem cells
  • Cord blood stem cells