Jacobs Journal of Cancer Science and Research

Immunotherapeutic Approach to Osteosarcoma

Published on: 2017-02-03


Osteosarcoma is a rare form of cancer that account for less than 0.2% of all cancers diagnosed in the United States. Unfortunately, the cause is unknown, but there have been several risks factors accused of causing the disease such as genetics, Paget disease, exposure to radiation or chemicals, and bone marrow transplants. Immunotherapy is a cancer treatment alternative to chemotherapy and radiation therapy. Its goal is to use a patient’s own immune system to fight the tumor. The patient’s immune system is stimulated by exposing synthetic immune molecules into their system. In this paper, we discuss the potential causes of osteosarcomas, the pathophysiology of the disease, and potential ways to cure the disease using different immunotherapy techniques.


Bone Cancer; Immunotherapy; Chondrosarcoma; Osteosarcoma