Surgical Skin Tumors in Neurofibromatosis 1 (NF1) at the Dakar Cancer Institute
Published on: 2018-11-02
Objectives: To evaluate the epidemiological, diagnostic and evolutionary aspects of surgical skin tumors associated with neurofibromatosis type 1, the cancer institute of Dakar. Patients and Methods: We performed a retrospective study of six (06) years (July 2009 - December 2015) on surgical skin manifestations in Neurofibromatosis 1 (NF1). Results: There were 8 cases of Nf1 according to the bethesda criteria associated with skin tumors requiring surgical management. We found 6 women and 2 men. The average age was 35.4 years. We noted 05 cases (71.4%) of royal tumors and 03 cases (28.5%) of malignant tumors. In functional terms, 1 case of neurofibroma obscuring it was found. We conducted two shoulder disarticulation and 1 mastectomy. neo adjuvant radiotherapy was performed in a case of axillary tumor. After a 48-month decline, 1 case of malignant nerve sheath died. Conclusion: Surgical skin tumors in nf1 are rare. Surgery plays an important functional role in the royal tumors and is very mutilating in malignant tumors.