Jacobs Journal of Cancer Science and Research

Level of Selenium of Children with Acute Lymphoblastic Leukemia (ALL)

*MH Mousazadeh
Department Of Chemistry, Amirkabir University Of Technology, Iran, Islamic Republic Of

*Corresponding Author:
MH Mousazadeh
Department Of Chemistry, Amirkabir University Of Technology, Iran, Islamic Republic Of
Email:mousazadeh@aut.ac.ir

Published on: 2019-04-02

Abstract

In the present study, we studied the serum concentration of Se, with different types of leukemia patients. Our investigation shows that there are grounds for further study of the use of special selenium compounds both for treatment as well as for preventive measures.

Keywords

Selenium; Antioxidant Leukemia; Atomic Absorption Spectrometry

Introduction

Selenium (Se) is an essential trace element having considerable and particular functions for human health because it is genetically encoded for which incorporation into proteins, as the constitutive part of selenocysteine, the 21st amino acid. Most se-proteins have been shown to have a wide range of pleiotropic effects, ranging from antioxidant to anti-inflammatory effects, particularly the families of glutathione peroxidases (GPxs) and thioredoxin reductases (TrxRs), but their precise mechanism is not understood absolutely currently. Despite the scarce knowledge of mechanism, a large number of laboratory and ecologic researches focused on the associations between selenium and human health have been completed, showing that Se is associated with several human diseases including cardiovascular disease, central nervous system disease, diabetes mellitus, but the results are inconsistent.