Jacobs Journal of Cell and Molecular Biology

MHC Genes Class I, Class Ii In Invertebrates: The Echinodermata

*Michel Leclerc
Immunology Of Invertebrates, University Of Orleans, France

*Corresponding Author:
Michel Leclerc
Immunology Of Invertebrates, University Of Orleans, France
Email:mleclerc45@gmail.com

Published on: 2019-05-22

Abstract

Keywords

Introduction

As C.A Janeway wrote in 2001 [1] The function of MHC molecules is to bind peptide fragments derived from pathogens and display them on the cell surface for recognition by the appropriate T cells. The consequences are almost always deleterious to the pathogen-virus-infected cells are killed, macrophages are activated to kill bacteria living in their intracellular vesicles, and B cells are activated to produce antibodies that eliminate or neutralize extracellular pathogens. Thus, there is strong selective pressure in favor of any pathogen that has mutated in such a way that it escapes presentation by an MHC molecule.