Jacobs Journal of Clinical Case Reports

Acute Leptosperosis Associated With Epstein - Barr virus: Case report.

Published on: 2019-02-12


Leptospirosis is an infectious disease of humans and animals; it is caused by corkscrew-shaped bacteria called Leptospira. Weil’s disease is the classic form of severe leptospirosis, and it is characterized by liver damage (causing jaundice), kidney failure, and bleeding. Leptospiral infection in humans causes signs and symptoms that can range from none to mild such as headaches, muscle pains, and fevers; too severe with bleeding from the lungs the most serious and life-threatening of all leptospirosis complications, additionally, the heart and brain can be affected ,meningitis of the outer layer of the brain, encephalitis of brain tissue. Most of the cases are mild leptospirosis, the rest experience severe disease. We present an isolated case of Weil’s disease and EBV in a 15-year-old girl, the girl was admitted to our department due to high fever, abdominal pain and vomiting, on evaluation she found to have jaundice, decreasing hemoglobin, increasing bilirubin with abnormal value of liver enzymes; other causes of disease were investigated and EBV infection and leptospirosis were determined by serologic tests. The patient’s status improved after she was started on antibiotics. Immunosuppression during active EBV infection has been reported previously, and therefore, this could have caused the severe symptoms after Leptospira infection in our case.