Jacobs Journal of Clinical Case Reports

Successful Treatment of Behcet’s Disease Utilizing Bacterial and Viral Antigens

Published on: 2017-10-25


Objective:To describe the successful therapy of a patient with Behcet’s disease using streptolysin O and other bacterial and viral antigens.
Methods:A 32 year-old man with a 24- year history of Behcet’s disease symptoms not alleviated by several standard treatments (methotrexate, azathioprine, and prednisone) is described. He was given a treatment regime that included antigens from Streptococcus,\other bacteria, viruses, and streptolysin O.
Results:After seven months treatment, the patient’s BD symptoms improved dramatically including almost total cessation of mouth andgenital ulcers, almost total disappearance of chronic pain, and significant increase in energy levels.
Conclusion:Treatment with antigens from Streptococcus and other common bacteria and streptolysin O may be useful in treating Behcet’s disease.


Behcet’s Disease; Chronic Fatigue; Streptolysin; Histamine; Streptococcus antigens