Jacobs Journal of Dentistry and Research

Antimicrobial Activity of Root Canal Filling Materials

*Maia Jikia
Department Of Dentistry, School Of Health ScienceS, University Of Georgia, Georgia, United States

*Corresponding Author:
Maia Jikia
Department Of Dentistry, School Of Health ScienceS, University Of Georgia, Georgia, United States

Published on: 2019-08-19


The antimicrobial activity of filling materials was studied to improve the quality of treatment of complicated caries in vitro. Resorcin-formalin cement Resodont (“Latus”, Ukraine) - ? 1; Endocort zinc oxide-eugenol cement (“Latus”, Ukraine) - No. 2; materials based on zinc oxide eugenol cement with dexamethasone: Endomethasone ivory (Septodont, France) - No. 3 and Endofil ("Produit Dentaires SA", Switzerland) - No. 4. To assess the antimicrobial activity of the studied materials, test microorganism strains were used: Staphylococcus aureus ATCC 25923, Enterococcus faecalis ATCC 6783, Candida albicans ATCC 885-653.


As a result of the study, it was established that filling materials have different antimicrobial activity. Resodont has the greatest antimicrobial activity on the test culture. Endomethason is active in relation to the test cultures studied, inferior to Resodont in its antimicrobial properties. Endocort and Endofil have less antimicrobial activity than Resodont and Endomethason, but have approximately equal growth retardation rates. It should be noted that with respect to Staphylococcus aureus, Endocort was found to be almost 1.5 times more active than Endofil.


The conducted studies confirm that the materials for filling of root canals by Resodont and Endocort (Latus, Ukraine) have a pronounced antibacterial effect. They are competitive with foreign sealers and are the materials of choice, having a significantly lower cost.


Endodontic Microbiology; Root Canal Treatment; Antimicrobial Activity of Sealers


Despite accumulated experience knowledge and modern abilities in endodontic, the percentage of failed treatment of complicated caries in Ukraine is quite high, main causes of unsatisfactory endodontic treatment are disorders of standards of irrigation and filling of root canals. Often dentists do not consider the features of filling materials for obturation. In endodontic practice there are number of root canal obturation techniques, each of them has its own advantages and disadvantages. Nowadays, most popular method among endodontists, is obturation of root canals with gutta-percha and sealer. According to many prominent researchers’ perfect sealer should not irritate the periodontal tissues, densely obturate root canals both in lateral and vertical directions, not let the sealer shrink in root canals, it should also have antibacterial effect, be hydrophobic, biocompatible, nontoxic and radiopaque. it should not affect the tooth color and at the same time should be able to polymerasequickly, should have good adhesive feature to the dentine and gutta-percha.