ABO and Rhesus D Blood Groups Distribution among Students in Usmanu Danfodiyo University Sokoto, North Western Nigeria
Published on: 2015-11-06
Background: There is ethnic variation in the prevalence of ABO and Rhesus D blood groups. This aim of this present study is to determine the distribution of ABO and Rhesus D blood group among students of African descent attending Usmanu Danfodiyo University in Sokoto North Western, Nigeria. Methods: ABO and Rhesus D phenotype of 250 consecutively -recruited students of Usmanu Danfodiyo University in Sokoto North Western, Nigeria was determined using standard tube techniques based on haemagglutination principle. Seraclone Anti- A, B, AB and D reagents (Bio Rad Medical Diagnostics, Germany) was utilized. Results: A total of two hundred and fifty students (250) apparently healthy students of African descent attending Usmanu Danfodiyo University in Sokoto North Western aged 18-35 years and mean age 26 ± 2.0 years made up of 145 males (58.0%) and 105 female (42.0%) constituted the subjects in this case study. The distribution of the ABO blood group and Rhesus D revealed that 103 (41.2%) were group O, 68 (27.2%) were group B, 63 (25.6%) were group A and 15 (6%) were group AB. Out the 250 subjects investigated, 223 (89.2%) were Rhesus positive and 105 (10.8%) were Rhesus negative. Our finding is consistent with the general formula O > B ≥ A > AB indicating a preponderance of phenotype B over A. We observed a significant difference in the distribution of O and B based on gender (p=0.01). Conclusion: The pattern of distribution of ABO blood groups among students in Sokoto is at variance with other populations particularly among Caucasians. Data derived from this study will help policy makers make evidenced –based decisions on optimum stocking of blood and blood products in Blood banks in the area, management of Haemolytic Transfusion Reaction and Haemolytic Disease of the Foetus and Newborn.