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Effect of Plasmapheresis on Treatment of Acute Pancreatitis in Infant with Familial Chylomicronemia

Jacobs Journal of Emergency Medicine

Effect of Plasmapheresis on Treatment of Acute Pancreatitis in Infant with Familial Chylomicronemia

Published on: 2017-01-26

Abstract

Familial chylomicronemia is a rare genetical disorder. (autosomal recessive)with incidence 1/ 1000,000 that there is difficulty in clearance serum content of triglyceride & cholesterol due to deficiency of Apo-B-lipoprotein lipase or lipoprotein lipase(LPL) or cofactor Apo-C II. Different between them is decreased the level of serum TG after prescription FFP in Apo-CII and without response in LPL deficiency. Clinical features are Hepatosplenomegaly, Pancreatitis attack, Xantem eruptions on limbs & buts, Paleness of retina (libemia reticolaris). We introduce a female baby 41 days old that referred by hyperlipidemia (TG=25000mg/dl & cholesterol=1500mg/dl) and acute pancreatitis attack and signs & symptoms denoting to familial chylomicronemia who treated by plasmapheresis.

Keywords

Plasmapherisis, Acute Pancreatitis, Familial Chylomicronemia