Jacobs Journal of Gastroenterology and Hepatology

Herbal Drugs-An approach for the Treatment of Liver Disorders

*Swapnil Pandey
Department Of Pharmacognosy, Varanasi College Of Pharmacy, Varanasi, India

*Corresponding Author:
Swapnil Pandey
Department Of Pharmacognosy, Varanasi College Of Pharmacy, Varanasi, India
Email:pankajmeen@rediffmail.com

Published on: 2019-05-16

Abstract

The liver is an amazingly complex organ which virtually affects every physiological process of the body. The liver is the largest glandular organ in body, and has more function than any other organs. Hepatic disorders which stem from a stressful life style, inappropriate eating habits and lack of exercise have become one of the major causes of morbidity and mortality in human being. The acute hepatic symptoms may be cured by some general prevention such as avoidance of constipation and balance between intake quantity of protein and disaccharides in normal food. An alternative and a progressively increasing adaptation is the use of herbal extracts. Many of the plant-based drugs show effective response to managing the hepatotoxicity and secondary symptoms of liver damage. While, the models used for conventional hepatotoxicity evaluation are still outdated, in the present review we have attempted to provide an updated information of the molecular pathogenesis and aspects for the role of herbal pharmacotherapy in alleviation of hepatic ailments. Furthermore, we have attempted to summarize the critical findings on hepatoprotective herbs over a period of last 20 years.

Keywords

Hepatotoxicity; Hepatoprotective herbs; Hepatic injury; Hepatic function test; Silybum marianum; Allium sativum

Introduction

Medicinal plants may serve as a vital source of potentially useful new compounds for the development of effective therapy to combat a variety of disease. Herbal medicine is used by about 80% of the world population primarily in the developing countries for primary health care. Ancient literatures also mention herbal therapy for age related diseases namely memory loss, osteoporosis, diabetic wounds, immune and liver disorder, etc. 1998. The Indian traditional medicine like Ayurveda, siddha and unani are predominantly based on the use of plant materials. Herbal drugs have gained importance and popularity in recent year because of their safety, efficacy and cost effectiveness [1].