Jacobs Journal of Gynecology and Obstetrics

Relationship in Prolactin and Tsh Serum Levels with Male Infertility

Published on: 2019-02-13


Context: Although studies to determinate and relate the prolactin and TSH serum levels with the female infertility. In men infertility those doesn’t exist.
Objective: To relate the prolactin and TSH serum levels in male patients who have a semen analysis, a complete record and are attended at the infertility clinic.
Materials and methods: An ambispective study, with a total of 85 male patients of infertility couples who attended the infertility clinic and had a semen analysis and a complete endocrinological profile were included to the statistical analysis comparing the results.
Results: A total 85 patients met the inclusion criteria: 8 of 85 patients with TSH: 2.5-3.9mU/mL, 6 patients TSH: >4mU/mL, 2 had TSH: <0.5mU/mL and 69 had TSH: 0.5-2.5. Patients in the prolactin group 8 of 85 had prolactin>20ng/dL and 77 had prolactin levels<20ng/dL. In the group of TSH 2.5- 3.9mU/mL the teratozoospermia were found to be higher than the group TSH: 0.5/2.5mU/mL (6% vs 37% respectively), although without statistical significance, in the group TSH>4mU/mL the teratozoospermia were higher (50%, p=0.006). In the group of prolactin>20ng/ dL teratozoospermia and asthenozoospermia were higher than the prolactin<20ng/dL without statistical significance (p=0.113 and p=0.353 respectively)
Conclusion: The TSH levels above 4 mU/mL are related to abnormalities in the sperm morphology. Prolactin levels greater than 20ng/dL does not show an association with alterations in sperm parameters.


Sperm gram; TSH; Prolactin; Hyperprolactinemia; Hypothyroidism; Hyperthyroidism; Male Infertility