Jacobs Journal of Neurology and Neuroscience

An Acute Cerebellar Syndrome. Who Is Involved?

Published on: 2018-01-18


Case Report: We report the case of a 79 year-old bipolar patient treated with Lithium who developed an acute cere-bellar syndrome following a Legionnellosis episode. Clinical evolution, biological exams, structural and functional imaging were all favoring a post-infectious disease.

Discussion: Cerebellar disorders in Legionnaire’s disease are considered an inflammatory process although patho-physiology remains poorly understood. Granting the recent studies on the role of lithium as neuropro-tective in neuroinflammation, we empirically hypothesized that lithium might have played a beneficial role in this case.

Conclusion: This case shows that FDG PET/CT can help confirm the diagnosis of post-Legionnella cerebellitis and should be easily prescribed in this indication. Furthermore, we suspect that Lithium might have a neu-roprotective effect in this post-infectious phenomena. Subarachnoid haemorrhage(SAH) accounts for approximately only 5% of strokes [1], yet occurs at a young age leading to lengthy burden. SAH outcomes research has rarely examined psychological outcomes, despite their prevalence and substantial contribution to recovery [2], and potentially to functional outcomes.


Cerebellar Disorders; Legionellosis; Cerebellar Neurodegeneration; Acute Ataxia; Neu-roinflammation