Jacobs Journal of Neurology and Neuroscience

Change in Mood and Functional Outcomes in the Year following Subarachnoid Haemorrhage and Comparison to Matched Controls

Published on: 2018-09-04

Abstract

Subarachnoid Haemorrhage (SAH) research rarely examines psychological outcomes, particularly in relation to functional recovery (e.g., Health Related quality of life HRQoL). This study describes mood and functional outcomes in the first year postSAH, compared to matched controls, and examined factors related to mood and function at 12-months. Thirty individuals with SAH and 29 age, gender and ethnicity matched controls participated. SAH-participants were assessed at 28-days, 6- and 12-months post-SAH on the Hospital Anxiety Depression Scale(HADS), General Health Questinonaire-28(GHQ-28), Short Form36(SF-36), modified Rankin Scale(mRS), and Barthel Index (BI). Despite good disability outcomes (mRS≤2; BI≥90) at each assessment, SAH participants exceeded cut-off on the GHQ-28 at 28-days, but not 6- or 12-months. At 6- and 12-months the SAH group scored significantly higher than controls on the HADS and GHQ-28, was significantly more disabled (mRS but not BI), and had significantly poorer HRQoL. From 28-days to 6-months, HADS depression scores and GHQ-28 somatic symptoms and social dysfunction scores reduced significantly while HADS anxiety and GHQ-28 total score did not change (p>.05). No significant changes were found for mood or HRQoL from 6- to 12-months (p>.05). Age, ethnicity, education, and SAH severity were not related to 12-month HRQoL (p>.05), while female gender, clipping, having previous stroke history, and worse overall mood were significantly related. Mood and HRQoL outcomes should be repeatedly assessed post-SAH. The current findings indicated that SAH survivors who have had a previous stroke and/or underwent surgical clipping during acute SAH intervention had worse emotional and physical HRQoL outcomes compared to those survivors who had not.

Keywords

Subarachnoid Haemorrhage; Mood; Quality Of Life; Matched Comparison