Jacobs Journal of Neurology and Neuroscience

Chronic Inflammatory Demyelinating Polyneuropathy Secondary to Hypereosinophilia: A Rare Case

Published on: 2018-08-24


A 16-year-old male with limb weakness, reduced muscle tone and absent reflexes was diagnosed with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) secondary to idiopathic hypereosinophilic syndrome (IHES). Oral corticosteroids decreased the eosinophil count but disease relapse and elevation of the eosinophil count occurred after the dose was tapered. However, organ dysfunction was responsive to intravenous immunoglobulin. The use of intravenous immunoglobulin for CIDP secondary to IHES has not been reported.


Idiopathic Hypereosinophilic Syndrome; Eosinophilia; Chronic Nflammatory Demyelinating Polyradiculoneuropathy; Corticosteroids; Immunoglobulin