Jacobs Journal of Ophthalmology

Ocular Manifestations in Alport Syndrome

*Anchal Thakur
Department Of Ophthalmology, Post Graduate Institute Of Medical Education And Research, India

*Corresponding Author:
Anchal Thakur
Department Of Ophthalmology, Post Graduate Institute Of Medical Education And Research, India
Email:thakur_anchal@yahoo.co.in

Published on: 2019-05-13

Abstract

Alport syndrome is a rare hereditary disorder with multi-organ involvement including the eyes, kidneys and ears. We report a 23-year-old male who demonstrated classical ocular manifestations associated with Alport syndrome. He presented with chief complaints of blurring of vision in the left eye over the past 3 months. T

Keywords

Introduction

Alport syndrome is a rare hereditary disorder with multi-organ involvement including the eyes, kidneys and ears. We report a 23-year-old male who demonstrated classical ocular manifestations associated with Alport syndrome. He presented with chief complaints of blurring of vision in the left eye over the past 3 months. The best corrected visual acuity was 20/40 and 20/60 in the right and left eye respectively. An oil droplet reflex was observed on retinoscopy in both eyes suggestive of anterior lenticonus. Slit lamp biomicroscopic examination of the anterior segment revealed conical bowing of the anterior surface of the crystalline lens in both eyes (Figure 1 and 2). There was anterior capsular cataract in the left eye. (Figure 2). Fundus examination revealed profuse, round, pale-yellow colored flecks in the macular region sparing the fovea suggestive of dot and fleck retinopathy (Figure 3 and 4). Systemically, the patient had a history of progressive sensorineural hearing loss since childhood and had undergone renal transplant 14 months back. A positive family history was revealed on examination of the mother and brother who had similar lenticular and retinal findings.