Journal of Molecular Biomarkers and Clinical Trials

Ambulatory Arterial Stiffness Index (AASI) and Antihypertensive Drug Effects: A Study with Spironolactone

Published on: 2016-08-31


Patients with essential hypertension have shown increased arterial stiffness. ABPM allows us to obtain AASI (Ambulatory Arterial Stiffness Index) through a mathematical formula (1-slope DBP/SBP) This index has many physiologic components (one of them is arterial stiffness), correlates well with Pulse Wave Velocity (PWV),and shows good prognostic value in normal and hypertensive populations: with increased AASI values, worse CV prognosis.


Ambulatory Arterial Stiffness Index, Antihypertensive Drug Effects, Spironolactone