Journal of Molecular Biomarkers and Clinical Trials

Rapidly Progressing Left Atrial Primary Undifferentiated Pleomorphic Sarcoma

*Dr. Abdelsalam Elhenawy
Department Of Cardiothoracic Surgery, People’s Hospital Of Ningxia Hui Autonomous Region, Yinchuan, China

*Corresponding Author:
Dr. Abdelsalam Elhenawy
Department Of Cardiothoracic Surgery, People’s Hospital Of Ningxia Hui Autonomous Region, Yinchuan, China
Email:aelhenaw@ualberta.ca

Published on: 2016-06-10

Abstract

Primary cardiac tumors are rare. Approximately, a quarter of those tumors are malignant and cardiac sarcomas account for 75% being the most common subtype of primary cardiac malignancies. A 61-year-old man was admitted to our hospital for progressive exertional cough, and dyspnea. Transthoracic echocardiography showed a large intra-cardiac mass originated from the roof of left atrium with a wide base. However, the histological diagnosis was a cardiac undifferentiated pleomorphic sarcoma. We present a case of primary undifferentiated pleomorphic sarcoma of the left atrium exhibiting very early recurrence after the first resections.

Keywords

Primary cardiac tumor, Sarcoma, Resection, Recurrence

Introduction

Primary cardiac tumors are extremely rare that most cardiac surgeons would not practice this disease sufficiently. In one autopsy report [1], the incidence is only 0.0001% to 0.0003%. Of these cardiac tumors, about a quarter is malignant with sarcoma being the most common subtype accounting for 75% of the malignant neoplasms [2]. More recently, in the largest published series [3], all subtypes of left atrial sarcomas incidence are 33% of the total primary cardiac sarcomas resected surgically. Recurrence is common. Herein, we reported the first recurrence of undifferentiated pleomorphic sarcoma within 34-day period post-surgery.