Volume 2 Issue 1

June 2016

Volume 2 Issue 1

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Research Article

Anti-Inflammatory Effects of Heparin: Do they Influence Murine Acute GvHD?

Holger Budde*, Lena Thieringer, Joachim Riggert, Tobias J Legler

Graft-versus-host disease (GvHD) is still one of the most challenging complications after allogeneic hematopoietic stem cell transplantation. Steroid-resistant or steroid-refractory patients with acute GvHD have limited therapeutic options and there is a strong demand in clinics for new therapeutic approaches. Due to the published anti-inflammatory effects of heparin, we hypothesized that either unfractionated (UFH) or low-molecular-weight heparin (LMWH) could be a novel treatment option for patients with acute GvHD.

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Research Article

Red Blood Cells on the Turin Shroud

Gérard Lucotte*

We have studied by SEM-EDX analysis the red blood cells (hematies) at the surface of the Turin shroud. Sample is a stickytape, triangular in form, that was applied on the Face area of the Turin shroud in 1978. We found on it twenty-five corpuscules that are red-blood cells, according to morphological and chemical criteria. Concerning morphology studied by SEM, one of them is a spherocyte, four are discocytes and three are ovalocytes, five are crenocytes and one is a hematy portion ; a total number of twenty seven hematies are piled up “en rouleaux”.

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Clinical research

Use of Physiological Modulators in the Management of Anemia due to Menstrual Blood Loss

Cornelli U*, Belcaro G, Fareed J

Heavy menstrual bleeding is a common problem among women of reproductive age which may affect between 3 % to 19 % of women depending upon ethnicity and race. The impact of menstrual blood flow and diet on iron deficiency in women have been previously reported. Usually dietary iron intake is considered insufficient to prevent anemia due to menstrual blood loss.

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