Effects of Anaerobic Exercise Training on S-Klotho in Young and Elderly
Moran Saghiv*, Michael Sagiv, David Ben-Sira
Anaerobic bouts can be limited by lactic acid levels in the blood and active muscles. It is characterized by exposing the subjects to a very high degree of sudden strenuous all-out exercise, Thus, increasing insulin-like growth factor-1 (IGF-1) levels in the blood, primarily due to a substantial major increase in plasma catecholamine concentrations. When reactive oxygen species production overwhelms the protection and repair mechanisms, the net effect is oxidative stress and oxidative damage of DNA, membrane lipids, and proteins.
Comparison between aerobic and anaerobic training influence on s-klotho blood levels following 60 min aerobic bout
Moran Saghiv*, David Ben-Sira, Michael Sagiv
Soluble-Klotho (s-Klotho) is a powerful longevity protein that has been linked to the prevention of muscle atrophy, osteopenia, and cardiovascular disease. S-Klotho is a transmembrane protein which can be cleaved, shed and act as a circulating hormone. Strenuous all-out exercise training increase lactic acid levels in the blood and active muscles and increase insulin- like growth factor-1 (IGF-1) levels in the blood, primarily due to a substantial major increase in plasma catecholamine concentrations.