Seismic Evaluation of Framed Structures Reinforced by FRP

Original Article

Seismic Evaluation of Framed Structures Reinforced by FRP

Corresponding author:

M.Sailaja, Department of Biochemistry, Institute of Genetics, Osmania University, Hyderabad-500017

Biochemistry is study of chemical processes in the living organisms that give rise to complexity of life. This field is closely related to molecular biology, the study of the molecular mechanisms by which genetic information encoded in DNA is able to result in the processes of life.

Jacobs Journal of Biochemistry focuses on publishing a complete and reliable source of information providing a bridge between disciplines in various areas of medicine and all aspects of biochemical processes, including the structure, function and dynamics of metabolic pathways, supra molecular complexes, enzymes, proteins, nucleic acids and small molecular components of organelles, cells and tissues, applied biochemistry, biochemistry of cell metabolism and the endocrine system, bioenergetics, biochemical mechanisms, the genetic code (DNA, RNA), protein synthesis, cell membrane transport and signal transduction.

Jacobs Journal of Biochemistry of Volume 1 Issue 1 published articles discussing the topics on – an effect on Liver and Renal Function Tests on Blood Storage with and Without Irradiation [1], and Thermodynamic and Kinetic Properties of Lactate Dehydrogenase in Red Muscle of the MesothermThunnusobesus [2].

Blood for transfusion is stored using additives to preserve and to prevent coagulation and is pre-irradiated with gamma radiation to prevent graft versus host disease in the recipient. Biochemical storage lesions are still observed in this blood. KiranDahiya. [1]., planned to observe the effect of storage on plasma urea, creatinine, uric acid, total protein, aspartate transaminase (AST),alanine transaminase (ALT) and lactate dehydrogenage (LDH) on 0, 3, 7, 14 and 21 days with and without prior irradiation.From results, the levels of LDH were found to change significantly with storage and on irradiation from the first day itself while statistically significant changes began to appear in the levels of uric acid, total protein and AST from 14 day onwards. This might be due to changes in the integral composition of the erythrocytic membrane and also due to oxidative stress. Thus, it is concluded that blood for transfusion should ideally be a fresh one or not older than a period of 14 days though further supportive studies is needed to validate this report.

Although a number of studies on enzyme activities in ectotherms have clarified adaptation to environmental temperature, mesotherms have not been investigated in detail. Bigeye tuna Thunnusobesus is a cold-blooded animal. However, they are mesothermic because they have a unique thermoregulatory system that maintains body temperature at 21–26°C. Chie Takahashi et al. [2]., characterized the kinetic and thermodynamics of lactate Dehydrogenase (LDH) in red muscle of T. obesus.The results indicate that the catalytic reaction (pyruvate reduction) of T. obesus LDH is more progressed than that of slime flounder and Japanese sandfish. The hypothesis that the activity and thermodynamics of skeletal muscle type LDH are highly conserved during animal evolution is confirmed in a mesotherm based on the present results. Thermal independence of Vmax/Km is also observed in T. obesus LDH.Hence, it is concluded that the LDH structure has adapted to the behavior of the fish to produce energy.

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  1. Kiran Dahiya, Deepika Dalal, Monica Verma, Veena Singh Ghalaut, PK Sehgal, Rakesh Dhankhar. Is there an Effect on Liver and Renal Function Tests on Blood Storage With and Without Irradiation.
  2. Chie Takahashi, TatsufumiGoto, Mizuki Nakagawa, Shigeyoshi Nakamura, Shun-IchiKidokoro, Hideki Wakui, and WataruNunomura. Thermodynamic and Kinetic Properties of Lactate Dehydrogenase in Red Muscle of the MesothermThunnusobesus

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