Volume 2 Issue 1
An Efficient Method for Rapid Establishment of Fibroblast-Like Cells from Horse Subcutaneous Adipose Tissue
M. Quamrul Islam*
Adipose-tissue derived stromal cells (ADSCs) are easily obtainable multipotent mesenchymal stem cells capable of differentiation into various cell lineages making it an attractive cell source for regenerative medicine. ADSC is generally isolated from subcutaneous adipose tissue by enzymatic digestion of biopsies followed by removal of undigested tissues and seeding of the dissociated cells onto plastic. This is an inefficient procedure where only a tiny fraction of cells are established in culture and rest of the cells are lost.
Bioactive Mediators Associated with Mesenchymal Stem Cells-Mediated Immunomodulation
Lukáš Zachar*, Darina Bačenková, Jindrich Soltys, Ján Rosocha
Human mesenchymal stem cells (MSCs) have gained the attention in the field of regenerative medicine and cell therapy due to the low immunogenicity, distinctive immunomodulatory properties and also for the large potential to differentiate into many cell lines with not only mesenchymal origin. Our knowledge of the reparative, regenerative and immunomodulatory properties of MSCs is advancing. At the present we have a very comprehensible understanding how the MSCs affects the immune system.