Volume 4 Issue 1
Invasive Fungal Disease in Acute Leukemia: Single Center Retrospective Study
James England MD1, Sahar Torabi PharmD2, Heidi Chen PhD3, Megan Freeman MD, PhD4, Stephen Strickland MD, MSCI5, Gowri Satyanarayana MD1*
Invasive fungal disease (IFD) is a significant complication in patients undergoing treatment for acute leukemia. Current guidelines recommend routine prophylactic antifungal use in patients who become neutropenic while undergoing chemotherapy treatment for acute leukemia. We performed a single-center retrospective study examining 223 adult patients with AML or ALL who underwent 712 individual chemotherapy sessions between July 1, 2012 and June 30, 2014. The overall incidence of IFD was 9%, with 77% proven and 23% probable cases based on EORTC/MSG criteria.