Volume 5 Issue 2
Factors Associated with Loss to Follow-up Among Acceptors of the Levonorgestrel-releasing Intrauterine System at A Public-sector Family Planning Clinic in Brazil
Laura Miranda, Tatiana Figueiredo, Anibal Faúndes and Luis Bahamondes
In view of its confirmed effectiveness and long-lasting action, the 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) [1-2] is recognized as one of the most effective long-acting reversible contraceptives (LARCs). The LNG-IUS has also been found to be effective for the treatment of heavy menstrual bleeding (HMB). In addition, the device has been successfully used for treating endometriosis-associated pain, dysmenorrhea, endometrial hyperplasia and cancer, although it remains off-label for these indications [3-5].
Catechol-O-Methyltransferase Val158Met polymorphism and susceptibility to Uterine Leiomyoma
Pradeep Kumar, Vandana Rai
Uterine leiomyomas (uterine fibroids) are the most common benign tumor in premenopausal women. Several studies invstigated catechol-O-methyltransferase (COMT) Val158Met polymorphism as risk factor for Uterine leiomyomas (ULM) but the results were inconclusive. The aim of present meta-analysis was to evaluate the association of Val158Met (COMT) polymorphism with ULM. Authors performed keyword search of the Pubmed, Springer Link, Science Direct and Google Scholar databases up to March 31,2018. A total of 15 studies that have investigated the association of Val158Met polymorphism with ULM were retrieved.
Assessment of compliance with periconceptual Folic acid supplements amongst pregnant women at a metropolitan Hospital
Melinda Stanton, Kassam Mahomed
Neural tube defects result from a failure of the neural tube to close during embryonic development. Neural tube closure begins on day 18 and is complete by day 28 afterfertilisation [1,2], therefore often before a woman even realises she is pregnant. There is clear evidence that women with a higher intake of folic acid (FA) in the peri-conceptual period (one month before and 3 months after conception) have a 70% decreased risk of NTD . As dietary intake cannot achieve the recommended levels of PFS for maximal NTD risk reduction, it is recommended that a supplement of 400 mcg folic acid should be taken during the peri conceptual period.
The Use of the Transabdominal Cerclage in Women with Congenital Malformations of the Reproductive Tract
Emma Mullen1*, Alex Ridout1, Andrew Shennan1
There are a vast spectra of reproductive tract malformations, many of which put women at increased risk of preterm birth. Improvements in identification and management of recurrent late miscarriages have been made and we propose that a regime of monitoring and appropriate intervention could benefit a much broader patient base, including those with congenital malformations. Many of these women have undergone surgical procedures to correct anatomical abnormalities; with the reconstructed tract alleviating the presenting symptoms but not necessarily providing a system compatible with term pregnancy.