Volume 5  Issue 3

Volume 5  Issue 3

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Original Research

Original Pupillometry in Patients with Leber Congenital Amaurosis: Feasibility Study and Residual Retinal Cell Function
Radwan Ajlan , Leah Wood, Irma Lopez, Ayesha Khan, and Robert K. Koenekoop*

Leber Congenital Amaurosis (LCA) (OMIM 204000) is a devastating, hereditary photoreceptor disease. It is estimated to be responsible for 5% of all inherited retinal disease and characterized by severe visual impairment at or near birth, wandering nystagmus, abnormal pupillary responses (amaurotic pupils), a severely decreased or absent electroretinogram (ERG), and high refractive errors. At least twenty retinal genes have currently been associated with LCA, en-coding retinal proteins that participate in a wide variety of retinal functions.

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Editor Note: Ophthalmology

Pallapolu P* Ph.D

Macular hole-related retinal detachment (MHRD) is a special type of rhegmatogenous retinal detachment (RRD) (occurs when a tear in the retina leads to fluid accumulation) and a common entity in highly myopic eyes. Here, Wenyan Peng et al. [1]., described in details a novel technique to demonstrate the applicability of using perfluorocarbon liquid (PFCL) – and brilliant blue G (BBG) – assisted technique for peeling of internal limiting membrane (ILM) during vitrectomy (removing small portions of the vitreous humor from the front structures of the eye) with macular hole-related retinal detachment (MHRD) surgery.

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